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Agno vs LiteLLM

Side-by-side comparison with live GitHub signals. Last updated May 16, 2026.

A

Agno

Build, run, and manage agentic software at scale with 38K+ stars

OSSFree
40.1Ktoday423
Visit GitHub
L

LiteLLM

Universal LLM API gateway for 200+ providers — 38K+ stars

OSSFree
47.2Ktoday385
Visit GitHub
MetricAgnoLiteLLM
GitHub Stars40.1K47.2K
Contributors423385
Last CommitMay 16, 2026May 16, 2026
Open Issues8983091
Licenseopen-sourceopen-source
Pricingopen-sourceopen-source
Free TierYesYes
Categoryframeworksframeworks
TrendingNoNo

Shared Tags

pythonopen-source

Only in Agno

agent-frameworkfastapimulti-agentorchestrationtool-usememoryragself-hosted

Only in LiteLLM

api-gatewaymulti-modelproxyload-balancing

About Agno

Agno is a full-stack platform for agentic software comprising three layers: a Python framework for building agents and teams with memory, knowledge, and 100+ tool integrations; a production-ready FastAPI runtime with 50+ APIs, horizontal scaling, native tracing, and human-in-the-loop approval workflows; and AgentOS, a control plane UI for monitoring and managing deployed agents. Supports per-user and per-session isolation, role-based access control, guardrails, evaluations, and immutable audit trails. All data stays in your database — no vendor lock-in.

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About LiteLLM

LiteLLM provides a unified OpenAI-compatible API for 200+ LLM providers (OpenAI, Anthropic, Google, Azure, AWS Bedrock, Ollama, and more). Use one interface to call any model, with built-in load balancing, fallbacks, spend tracking, and rate limiting. Essential infrastructure for multi-model agent systems.

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