Agno vs AutoGen
Side-by-side comparison with live GitHub signals. Last updated May 16, 2026.
| Metric | Agno | AutoGen |
|---|---|---|
| GitHub Stars | 40.1K | 58.1K |
| Contributors | 423 | 445 |
| Last Commit | May 16, 2026 | Apr 15, 2026 |
| Open Issues | 898 | 823 |
| License | open-source | open-source |
| Pricing | open-source | open-source |
| Free Tier | Yes | Yes |
| Category | frameworks | frameworks |
| Trending | No | No |
Shared Tags
Only in Agno
Only in AutoGen
About Agno
Agno is a full-stack platform for agentic software comprising three layers: a Python framework for building agents and teams with memory, knowledge, and 100+ tool integrations; a production-ready FastAPI runtime with 50+ APIs, horizontal scaling, native tracing, and human-in-the-loop approval workflows; and AgentOS, a control plane UI for monitoring and managing deployed agents. Supports per-user and per-session isolation, role-based access control, guardrails, evaluations, and immutable audit trails. All data stays in your database — no vendor lock-in.
View full listingAbout AutoGen
AutoGen is Microsoft's open-source framework for building multi-agent conversational systems where agents can converse with each other and with humans to solve complex tasks. Agents are highly customizable and can use LLMs, tools, and human input in flexible combinations. The framework supports group chats, nested conversations, and code execution sandboxes, making it well-suited for coding assistants, research automation, and enterprise agentic workflows. AutoGen Studio provides a no-code UI for prototyping agent systems visually.
View full listing